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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. Hemolytic transfusion reactions seldom occur because the incidence of unexpected antibodies in random patients is relatively low, e.g., 3-5% is sometimes cited.
Being transfused with O Rh negative RBC is irrelvant if you have an unexpected antibody like anti-K or anti-c.
Incompatible red cells may "bleed out" but only if bleeding is brisk. Even then, a hemolytic reaction may occur later once the patient's antibody rebounds and destroys remaining antigen-positive donor red cells.
It's true that some patients have only cold-reactive antibodies that will not react at body temperature. But this does not explain why warm-reactive red cell antibodies cause few reactions Why do so few patients transfused with un-crossmatched red cells in an emergency experience a hemolytic transfusion reaction? Select the one best reason.

A) The incidence of unexpected red cell antibodies is relatively low.
B) They usually receive group O Rh negative red cells; a hemolytic transfusion reaction will never occur if O Rh-negative red cells are transfused.
C) Some patients have cold-reactive antibodies that will not react at body temperature.
D) They hemorrhage so severely that incompatible donor red cells "bleed out" before a reaction occurs.

2. Deviations from Beer's Law are caused by:

A) very high concentrations of substance being measured in a colorimetric reaction
B) very low concentration of absorbing material
C) polychromatic light
D) stray light

3. Ammonium biurate crystalsare typically round, irregularly spiked and yellow-brown in color.
A microscopic examination of a normal urine pH 8.0 shows 2+ yellow-brown thorny spheres which are MOST probably:

A) amorphous urate crystals
B) crenated red cells
C) ammonium biurate crystals
D) waxy casts
E) ampicillin crystals

4. MLTs must be provided with free immunization for:

A) hepatitis A
B) hepatitis B
C) hepatitis C
D) HIV

5. The thrombin time (TT) involves the addition thrombin to platelet poor plasma to stimulate the clotting process. It reflects ability of the patient to convert fibrinogen to fibrin but is also sensitive to the presence of inhibitors that may be present in the plasma, like heparin. Therefore, it can be used to measure the effects of heparin on a coagulation sample.
This assay would be used to help rule-out heparin contamination in a coagulation sample:

A) PT
B) APTT
C) Thrombin time
D) Protein C assay

Solutions: